ELISA ABCB11 anti-

Quantity :50µL Clone Number: Aliases:ABC member 16; MDR/TAP subfamily antibody; ABC16 antibody; ABCB1 antibody; Abcb11 antibody; ABCBB_ antibody; ATP binding cassette sub family B (MDR/TAP) member 11 antibody; ATP binding cassette sub family B member 11 antibody; ATP-binding cassette sub-family B member 11 antibody; Bile salt export pump antibody; BRIC2 antibody; Bsep antibody; PFIC 2 antibody; PFIC2 antibody; PGY4 antibody; progressive familial intrahepatic cholestasis 2 antibody; Sister of P glycoprotein antibody; Spgp antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O95342 Immunogen:Synthetic peptide of ABCB11 Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, IHC; ELISA:1:1000-1:5000, IHC:1:15-1:50 Background:The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecµLes across extra- and intra-cellµLar membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in mµLtidrµg resistance. The protein encoded by this gene is the major canalicµLar bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ABCB11 Research Areas:Cancer;Metabolism;Signal transduction