ELISA AANAT anti-

Quantity :50µL Clone Number: Aliases:AA-NAT antibody; Aanat antibody; Aralkylamine N-acetyltransferase antibody; Arylalkylamine N acetyltransferase antibody; Serotonin acetylase antibody; Serotonin N-acetyltransferase antibody; SNAT antibody; SNAT_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q16613 Immunogen:Fusion protein of AANAT Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, IHC; ELISA:1:1000-1:5000, IHC:1:50-1:200 Background:The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penµLtimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regµLated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:AANAT Research Areas:Neuroscience?Cancer;Metabolism