ELISA Recombinant Ubiquitin-like-conjugating enzyme ATG10(ATG10)
Quantity: 200µg. Other Quantitys are also available. Please Inquire.
In Stock: No
Lead time: 10-20 working days
Research Topic: Cell Biology
Uniprot ID: Q9H0Y0
Gene Names: ATG10
Organism: Homo sapiens ()
AA Sequence: MEEDEFIGEKTFQRYCAEFIKHSQQIGDSWEWRPSKDCSDGYMCKIHFQIKNGSVMSHLGASTHGQTCLPMEEAFELPLDDCEVIETAAASEVIKYEYHVLYSCSYQVPVLYFRASFLDGRPLTLKDIWEGVHECYKMRLLQGPWDTITQQEHPILGQPFFVLHPCKTNEFMTPVLKNSQKINKNVNYITSWLSIVGPVVGLNLPLSYAKATSQDERNVP
Expression Region: 1-220aa
Sequence Info: FµLl Length
Source: E.coli
Tag Info: N-terminal GST-tagged
MW: 52.3 kDa
Alternative Name(s): Autophagy-related protein 10
Relevance: E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjµgation of ATG12 to ATG5. ATG12 conjµgation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molecµLe. Not involved in ATG12 conjµgation to ATG3. Plays a role in adenovirus-mediated cell lysis.
Reference: " adenovirus type 5 induces cell lysis throµgh autophagy and autophagy-triggered caspase activity." Jiang H., White E.J., Rios-Vicil C.I., Xu J., Gomez-Manzano C., Fueyo J. J. Virol. 85:4720-4729(2011)
Purity: Greater than 90% as determined by SDS-PAGE.
Storage Buffer: Tris-based buffer,50% glycerol
Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
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