ELISA Recombinant U1 small nuclear ribonucleoprotein 70 kDa(SNRNP70),partial

Quantity: 200µg. Other Quantitys are also available. Please Inquire. In Stock: No Lead time: 10-20 working days Research Topic: Epigenetics and Nuclear Signaling Uniprot ID: P08621 Gene Names: SNRNP70 Organism: Homo sapiens () AA Sequence: MTQFLPPNLLALFAPRDPIPYLPPLEKLPHEKHHNQPYCGIAPYIREFEDPRDAPPPTRAETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRH Expression Region: 1-210aa Sequence Info: Partial Source: E.coli Tag Info: N-terminal 6xHis-tagged MW: 28.7 kDa Alternative Name(s): RNPU1Z, RPU1, SNRP70, U1AP1 Relevance: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRNP70 binds to the loop I region of U1-snRNA. The truncated isoforms cannot bind U1-snRNA. Reference: "The U1-70K snRNP protein: cDNA cloning, chromosomal localization, expression, alternative splicing and RNA-binding." Spritz R.A., Strunk K., Surowy C.S., Hoch S.O., Barton D.E., Francke U. Nucleic Acids Res. 15:10373-10391(1987) Purity: Greater than 85% as determined by SDS-PAGE. Storage Buffer: Tris-based buffer，50% glycerol Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.