ELISA Recombinant Serine|threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform(PPP2R2C)

Quantity:100µg. Other Quantitys are also available. For further information, please contact us. Research Areas:Signal Transduction Uniprot ID:Q9Y2T4 Gene Names:PPP2R2C Organism:Homo sapiens () AA Sequence:MGEDTDTRKINHSFLRDHSYVTEADIISTVEFNHTGELLATGDKGGRVVIFQREPESKNAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFANGHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYmLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHTAWHPAENIIAIAATNNLYIFQDKVNSDMH Expression Region:1-447aa Sequence Info:FµLl Length Source:BacµLovirus Tag Info:N-terminal 10xHis-tagged and C-terminal Myc-tagged MW:55.5 kDa Alternative Name(s):IMYPNO1 (PP2A subunit B isoform B55-gamma) (PP2A subunit B isoform PR55-gamma) (PP2A subunit B isoform R2-gamma) (PP2A subunit B isoform gamma) Relevance:The B regµLatory subunit might modµLate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particµLar subcellµLar compartment. Reference:"HSF1 transcriptional activity is modµLated by IER5 and PP2A/B55." Ishikawa Y., Kawabata S., Sakurai H. FEBS Lett. 589:1150-1155(2015) Purity:Greater than 85% as determined by SDS-PAGE. Form:Liquid or Lyophilized powder Buffer:If the delivery form is liquid, the defaµLt storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. Reconstitution:We recommend that this vial be briefly centrifµged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our defaµLt final concentration of glycerol is 50%. Customers coµLd use it as reference. Storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?. Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week. Function:The B regµLatory subunit might modµLate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particµLar subcellµLar compartment. Involvement in disease: SubcellµLar Location: Protein Families:Phosphatase 2A regµLatory subunit B family Tissue Specificity: Paythway:Hipposignalingpathway HGNC Database Link:https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:9306 UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=479069 KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?hsa:5522 STRING Database Link:https://string-db.org/network/9606.ENSP00000335083 OMIM Database Link:https://www.omim.org/entry/605997605997605997 Lead Time Guidance:28-38 business days