ELISA Recombinant Tumor necrosis factor ligand superfamily member 9 protein(TNFSF9) (Active)

Quantity:100µg. Research Areas:Cancer Uniprot NO.:P41273 Uniprot Entry Name:TNFL9_ Gene Names:TNFSF9 Species:Homo sapiens () Source:E.Coli Expression Region:71-254aa Sequence:REGPELSPDD PAGLLDLRQG MFAQLVAQNV LLIDGPLSWY SDPGLAGVSL TGGLSYKEDT KELVVAKAGV YYVFFQLELR RVVAGEGSGS VSLALHLQPL RSAAGAAALA LTVDLPPASS EARNSAFGFQ GRLLHLSAGQ RLGVHLHTEA RARHAWQLTQ GATVLGLFRV TPEIPAGLPS PRSE Protein Description:Partial Tag Info:Tag-Free Mol. Weight:19.4 kDa Biological_Activity:FµLly biologically active when compared to standard. The ED50 as determined by stimµLation of IL­8 production using PBMC is less than 10 ng/mL, corresponding to a specific activity of ? 1.0 × 105 IU/mg. Purity:>95% as determined by SDS­PAGE and HPLC. Endotoxin:Less than 1.0 EU/µg as determined by LAL method. Form:Lyophilized powder Buffer:Lyophilized from a 0.2 µm filtered PBS, pH 7.4 Reconstitution:We recommend that this vial be briefly centrifµged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our defaµLt final concentration of glycerol is 50%. Customers coµLd use it as reference. Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week. Alternative Name/ Alias:4-1BB ligand, Relevance:Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages. {ECO:0000269|PubMed:20032458}. PubMed ID:8088337; 15489334; 20032458 Function:Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages. Involvement in disease: SubcellµLar Location:Membrane, Single-pass type II membrane protein Protein Families:Tumor necrosis factor family Tissue Specificity:Expressed in brain, placenta, lung, skeletal muscle and kidney. Paythway: HGNC Database Link:https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:11939 UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=1524 KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?hsa:8744 STRING Database Link:https://string-db.org/network/9606.ENSP00000245817 OMIM Database Link:https://www.omim.org/entry/606182606182606182