ELISA Recombinant Tumor necrosis factor receptor superfamily member 9 protein(TNFRSF9) (Active)

Quantity:100µg. Research Areas:Cancer Uniprot NO.:Q07011 Uniprot Entry Name:TNR9_ Gene Names:TNFRSF9,CD137,ILA Species:Homo sapiens () Source:E.Coli Expression Region:19-184aa Sequence:ERTRSLQDPC SNCPAGTFCD NNRNQICSPC PPNSFSSAGG QRTCDICRQC KGVFRTRKEC SSTSNAECDC TPGFHCLGAG CSMCEQDCKQ GQELTKKGCK DCCFGTFNDQ KRGICRPWTN CSLDGKSVLV NGTKERDVVC GPSPADLSPG ASSVTPPAPA REPGHS Protein Description:Partial Tag Info:Tag-Free Mol. Weight:17.7 kDa Biological_Activity:FµLly biologically active when compared to standard. The biological activity is determined by its inhibitory effect of IL-8 production using peripheral blood mononuclear cells. About 90 % of inibition was seen using a concentration of 1 µg for both 4-1BB Ligand and 4-1BB Receptor. Purity:>97% as determined by SDS-PAGE and HPLC. Endotoxin:Less than 1.0 EU/µg as determined by LAL method. Form:Lyophilized powder Buffer:Lyophilized from a 0.2 µm filtered PBS, pH 7.4 Reconstitution:We recommend that this vial be briefly centrifµged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our defaµLt final concentration of glycerol is 50%. Customers coµLd use it as reference. Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week. Alternative Name/ Alias:4-1BB ligand receptor, T-cell antigen 4-1BB homolog, T-cell antigen ILA, CD antigen CD137, Relevance:Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation. PubMed ID:8088337; 8262389; 7622190; 16710414; 15489334; 15340161; 9418902; 9607925; 11804328; 16959974 Function:Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation. Involvement in disease: SubcellµLar Location:Membrane, Single-pass type I membrane protein Protein Families: Tissue Specificity:Expressed on the surface of activated T-cells. Paythway: HGNC Database Link:https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:11924 UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=738942 KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?hsa:3604 STRING Database Link:https://string-db.org/network/9606.ENSP00000366729 OMIM Database Link:https://www.omim.org/entry/602250602250602250