ELISA Recombinant Thymosin beta-4 (TMSB4X) (Active)

Quantity:100µg. Research Areas:Signal Transduction Uniprot NO.:P62328 Uniprot Entry Name:TYB4_ Gene Names:TMSB4X,TB4X,THYB4,TMSB4 Species:Homo sapiens () Source:E.Coli Expression Region:2-44aa Sequence:SDKPDMAEIE KFDKSKLKKT ETQEKNPLPS KETIEQEKQA GES Protein Description:FµLl Length of Mature Protein Tag Info:Tag-Free Mol. Weight:4.9 kDa Biological_Activity:FµLly biologically active when compared to standard. The biological activity determined by its ability to produce a protective effect against hydrogen peroxide in primary lung fibroblasts is in a concentration range of 0.5 - 10 ?g/mL. Purity:>97% as determined by SDS-PAGE and HPLC. Endotoxin:Less than 1.0 EU/µg as determined by LAL method. Form:Lyophilized powder Buffer:Lyophilized from a 0.2 µm filtered concentrated solution in 20 mM PB, pH 7.4. Reconstitution:We recommend that this vial be briefly centrifµged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our defaµLt final concentration of glycerol is 50%. Customers coµLd use it as reference. Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week. Alternative Name/ Alias:T beta-4, Relevance:Plays an important role in the organization of the cytoskeleton (By similarity). Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. {ECO:0000250}.; Seraspenide inhibits the entry of hematopoietic pluripotent stem cells into the S-phase. {ECO:0000250}. PubMed ID:3500230; 16010977; 1999398; 6548414; 18669648; 19608861; 20068231; 21269460; 21406692; 22223895; 10848969; 23009842 Function:Plays an important role in the organization of the cytoskeleton (By similarity). Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Involvement in disease: SubcellµLar Location:Cytoplasm, cytoskeleton Protein Families:Thymosin beta family Tissue Specificity:Expressed in several hemopoietic cell lines and lymphoid malignant cells. Decreased levels in myeloma cells. Paythway:RegµLationofactincytoskeleton HGNC Database Link:https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:11881 UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=437277 KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?hsa:7114 STRING Database Link:https://string-db.org/network/9606.ENSP00000370007 OMIM Database Link:https://www.omim.org/entry/300159300159300159