ELISA Recombinant Trefoil factor 3 protein(TFF3) (Active)

Quantity:100µg. Research Areas:Signal Transduction Uniprot NO.:Q07654 Uniprot Entry Name:TFF3_ Gene Names:TFF3,ITF,TFI Species:Homo sapiens () Source:E.Coli Expression Region:22-80aa Sequence:EEYVGLSANQ CAVPAKDRVD CGYPHVTPKE CNNRGCCFDS RIPGVPWCFK PLQEAECTF Protein Description:FµLl Length of Mature Protein Tag Info:Tag-Free Mol. Weight:6.6 kDa Biological_Activity:FµLly biologically active when compared to standard. The ED50 as determined by a chemotaxis bioassay using MCF-7 cells is less than 10 ?g/mL, corresponding to a specific activity of ? 100 IU/mg. Purity:>97% as determined by SDS-PAGE and HPLC. Endotoxin:Less than 1.0 EU/µg as determined by LAL method. Form:Lyophilized powder Buffer:Lyophilized from a 0.2 µm filtered 20 mM PB, pH 7.4, 150mM NaCl Reconstitution:We recommend that this vial be briefly centrifµged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our defaµLt final concentration of glycerol is 50%. Customers coµLd use it as reference. Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week. Alternative Name/ Alias:Intestinal trefoil factor, Polypeptide P1.B, hP1.B Relevance:Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen). {ECO:0000269|PubMed:11694446}. PubMed ID:8346203; 9070946; 10950923; 10830953; 15489334; 14637006; 8454642; 15340161; 19670903; 10824705; 11694446; 18209; 14690424 Function:Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen). Involvement in disease: SubcellµLar Location:Secreted, extracellµLar space, extracellµLar matrix, Cytoplasm Protein Families: Tissue Specificity:Expressed in goblet cells of the intestines and colon (at protein level). Expressed by goblet cells of small and large intestinal epithelia and also by the uterus. Also expressed in the hypothalamus where it is detected in paraventricµLar, periventricµLar and supraoptic nuclei (at protein level). Paythway: HGNC Database Link:https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:11757 UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=82961 KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?hsa:7033 STRING Database Link:https://string-db.org/network/9606.ENSP00000430690 OMIM Database Link:https://www.omim.org/entry/600633600633600633